The thing that might drive you craziest about going to work as a new mom is purely the logistics of the thing. Sometimes it may feel like both you and your partner need to be in about five different places at the same time. Whether you're working full- or part-time, reconciling your professional schedule with your childcare needs probably seems like a full-time job of its own.
What's the secret? It's simple, but true: communication. If you're in a relationship, you need to sit down with your partner and talk about what you can handle doing and what you can't. If you have family members or a nanny or babysitter helping you, you need to communicate what your expectations are. And, lastly, you need to talk to your boss about your schedule, too.
Some other tricks of the trade from moms in the know? Get a giant calendar you can write all over and devise a system of organization that works for you. Remember: You can't be everywhere at once -- it's OK to delegate.